Autophagy and sustainable health
Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells “Auto” means self and “phagy” means eat. So the literal meaning of autophagy is “self-eating
“It is recycling and cleaning at the same time, just like hitting a reset button to your body. Plus, it promotes survival and adaptation as a response to various stressors and toxins accumulated in our cells.
The main benefits of autophagy seem to come in the form of anti-aging principles. It’s best known as the body’s way of turning the clock back and creating younger cells. that in times of starvation, autophagy keeps the body going by breaking down cellular material and reusing it for necessary processes. At the cellular level, autophagy include:
- removing toxic proteins from the cells that are attributed to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease
- recycling residual proteins
- providing energy and building blocks for cells that could still benefit from repair
- on a larger scale, it prompts regeneration and healthy cells
Autophagy declines as we age, so this means cells that no longer work or may do harm are allowed to multiply, which is the MO of cancer cells
Possibility that autophagy may lower the risk of cancer.
Diet changes that can boost autophagy Fasting is [the] most effective way Trusted Source to trigger autophagy.
“Ketosis, a diet high in fat and low in carbs brings the same benefits of fasting without fasting, like a shortcut to induce the same beneficial metabolic changes,” she adds. “By not overwhelming the body with an external load, it gives the body a break to focus on its own health and repair.”
In the keto diet, you get about 75 percent of your daily calories from fat, and 5 to 10 percent of your calories from carbs. ketosis can also cause starvation-induced autophagy, which has neuroprotective functions. Low glucose levels occur in both diets and are linked to low insulin and high glucagon levels,” explains Petre. And glucagon level is the one that initiates autophagy.
“When the body is low on sugar through fasting or ketosis, it brings t
physical exercise may induce autophagy in organs that are part of metabolic regulation processes.